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Rabbit Anti-SKIP/Cy5.5 Conjugated antibody (bs-17506R-Cy5.5)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17506R-Cy5.5
英文名稱1 Rabbit Anti-SKIP/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的SKIP蛋白抗體
別    名 43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Function:
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.

Subcellular Location:
Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles.

Tissue Specificity:
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.

Similarity:
Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.

Database links:

Entrez Gene: 51763 Human

Entrez Gene: 19062 Mouse

Entrez Gene: 287533 Rat

Omim: 607875 Human

SwissProt: Q9BT40 Human

SwissProt: Q8C5L6 Mouse

Unigene: 632238 Human

Unigene: 1458 Mouse

Unigene: 7440 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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