吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲日本无码一区二区三区四区卡,国产麻豆剧传媒精品国产av
Rabbit Anti-phospho-Mre11 (Ser678)/BF594 Conjugated antibody (bs-17752R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17752R-BF594
英文名稱1 Rabbit Anti-phospho-Mre11 (Ser678)/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的磷酸化DNA損傷關(guān)鍵蛋白Mre11抗體
別    名 Mre11 (phospho S678); p-Mre11 (phospho S678); AT like disease; Ataxia telangiectasia disorder like; ATLD; DNA recombination and repair protein; Double strand break repair protein MRE11A; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; meiotic recombination (S. cerevisiae) 11 homolog A; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A (S. cerevisiae); Meiotic recombination 11 homolog A; MmMRE11A; Mre 11; MRE 11a; MRE 11b; MRE11 homolog 1; MRE11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11 homolog A; MRE11_HUMAN; MRE11A; MRE11b; OTTHUMP00000236830; OTTHUMP00000236831; OTTHUMP00000236832; OTTHUMP00000236833.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Mre11 around the phosphorylation site of Ser678
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.

Subcellular Location:
Nucleus. Localizes to discrete nuclear foci after treatment with genotoxic agents.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Defects in MRE11A are a cause of ataxia telangiectasia-like disorder (ATLD) [MIM:604391]. ATLD is a disease with the same clinical feature than ataxia-telangiectasia but with a somewhat milder clinical course.

Similarity:
Belongs to the MRE11/RAD32 family.

Database links:

Entrez Gene: 4361 Human

Omim: 600814 Human

SwissProt: P49959 Human

Unigene: 192649 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产乡下妇女做爰| 无码日韩精品一区二区免费暖暖| 玩弄JAPAN白嫩少妇HD小说| 国产精品久久久久久吹潮| 亂倫近親相姦中文字幕| AA片在线观看视频在线播放| 国产精品人人做人人爽人人添 | 欧美日韩欧美| 大白肥妇BBVBBW高潮| 人妻 丝袜美腿 中文字幕 | 国产精品宅男擼66M3U8| 国产精品无码久久av| 无码人妻少妇伦在线电影| 日韩视频在线观看| 亚洲国产成人精品无码区在线观看| 开心色| 无码JK粉嫩小泬在线观看欧美| 成人小说亚洲一区二区三区| 久久久婷婷五月亚洲97号色| 色欲AV伊人久久大香线蕉影院| 久久久久99精品成人片| 日日噜噜噜夜夜爽爽狠狠| 无遮挡国产高潮视频免费观看| 亚洲精品国产电影| 成人精品视频99在线观看免费| 一本久道中文无码字幕AV| 色琪琪女色窝77777| 精品久久久久久无码中文字幕一区| 性欧美XXXX| 欧美三级在线播放| 国产SM主人调教女M视频| 麻豆国产精品色欲AV亚洲三区| 亚洲精品午夜国产VA久久成人| 丝袜老师办公室里做好紧好爽| 精品国产成人亚洲午夜福利| 女人扒开屁股爽桶30分钟| 亚洲精品乱码久久久久蜜桃| 亚洲精品国产成人| 精品人伦一区二区三区蜜桃小说 | av片在线观看免费| 国产精品亚洲LV粉色|