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Rabbit Anti-HVCN1/FITC Conjugated antibody (bs-18109R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18109R-FITC
英文名稱1 Rabbit Anti-HVCN1/FITC Conjugated antibody
中文名稱 FITC標記的氫離子電壓門控通道蛋白1抗體
別    名 HV 1; HV1; HVCN 1; HVCN1; HVCN1_HUMAN; Hydrogen voltage gated channel 1; Hydrogen voltage-gated channel 1; Voltage gated hydrogen channel 1; Voltage sensor domain only protein; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1; VSOP.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HVCN1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.

Subcellular Location:
Membrane.

Tissue Specificity:
Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen.

Similarity:
Belongs to the hydrogen channel family.

Database links:

Entrez Gene: 84329 Human

Entrez Gene: 74096 Mouse

Omim: 611227 Human

SwissProt: Q96D96 Human

SwissProt: Q3U2S8 Mouse

Unigene: 211511 Human

Unigene: 334637 Human

Unigene: 28804 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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