吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
H漫在线观看,少妇激情一区二区三区视频
Rabbit Anti-NFIP1/PE-Cy7 Conjugated antibody (bs-19058R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19058R-PE-Cy7
英文名稱1 Rabbit Anti-NFIP1/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的乳腺癌相關(guān)蛋白SGA 1M抗體
別    名 0610010M22Rik; Breast cancer associated protein SGA 1M; Breast cancer-associated protein SGA-1M; MGC10924; N4WBP5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; NEDD4 WW domain binding protein 5; NEDD4 WW domain-binding protein 5; NFIP1_HUMAN; Putative MAPK activating protein PM13; Putative MAPK-activating protein PM13; Putative NF kappa B activating protein 164; Putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK activating protein; Putative NFKB and MAPK-activating protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NFIP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008]

Function:
Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation (By similarity). In cortical neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell growth rate.

Subunit:
Forms heterodimers with NDFIP2. Interacts with several E3 ubiquitin-protein ligases, including NEDD4, NEDD4L and WWP2. Interacts with ITCH, U2SURP and WWP2 By similarity. The interaction with NEDD4, NEDD4L and ITCH leads to relocalization of these proteins to exosomes and eventually to exosomal secretion. Interacts with SLC11A2/DMT1. Interacts with PTEN. May interact with phosphorylated EGFR.

Subcellular Location:
Endosome membrane. Golgi apparatus membrane. Secreted. Detected in exosomes and secreted via the exosomal pathway.

Tissue Specificity:
Widely expressed. Higher levels are detected in cerebellum, pituitary, thalamus, kidney, liver, testis, salivary glands and placenta. Also expressed in fetal brain, kidney and lung.

Post-translational modifications:
Ubiquitinated by NEDD4 and ITCH; mono-, di- and polyubiquitinated forms are detected. Ubiquitination regulates its degradation.
Undergoes transient tyrosine phosphorylation following EGF stimulation, most probably by catalyzed by SRC. Phosphorylation SRC is enhanced in the presence of NDFIP2 which may act as a scaffold to recruit SRC to NDFIP1.

Database links:

Entrez Gene: 80762 Human

Entrez Gene: 65113 Mouse

Entrez Gene: 291609 Rat

Omim: 612050 Human

SwissProt: Q9BT67 Human

SwissProt: Q8R0W6 Mouse

SwissProt: Q5U2S1 Rat

Unigene: 653510 Human

Unigene: 9788 Human

Unigene: 102496 Mouse

Unigene: 59254 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
韩国精品一区二区三区无码视频| 久久天天躁狠狠躁夜夜躁2014| 亚洲色无码A片一区二区潘甜甜| 中文字幕精品av乱码在线| 久久天天躁狠狠躁夜夜AV| 99精品人妻少妇一区二区| 久久亚洲AV成人无码国产| AV下页| 一炕四女被窝交换啪啪| 粉嫩av国产一区二区三区| 国产真实乱对白精彩| 精品熟人妻一区二区三区四区不卡| 精品亚洲成A人7777在线观看| 办公室双腿打开揉弄高潮淑芬| 精品国产污污免费网站AⅤ| 免费观看a级片| 欧美性猛交XXXX黑人| 囯产精品一品二区三区| AV电影网站| 亚洲精品WWW久久久久久| 色视频WWW在线播放国产人成| 中文在线最新版天堂| 亚洲AV无码专区国产乱码电影| 中国A级毛片免费观看| 国内精品视频一区二区三区八戒| 青青草视频在线观看| 色综合久久久久综合99 | 人人爽久久涩噜噜噜AV| 国产精品视频一区二区三区不卡 | japanese老熟妇乱子伦视频| 久久ER99热精品一区二区| 英语老师的小兔子好大好软水| 国产亚洲精久久久久久无码| 宝贝你的奶好大我想吃第一章| 国精产品一区二区三区有限公司 | 国产精品久久久久久一区二区三区 | 久久久亚洲精华液精华液精华液| 熟妇人妻久久中文字幕| 免费观看黄色电影| 久久久久99人妻一区二区三区| 老同学3免费完整版在线观看|