吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  人才招聘  關于我們  聯(lián)系我們
国产成人无码综合亚洲日韩 ,色婷婷综合久久久久中文一区二区 ,欧美性猛交XXXX乱大交蜜桃
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-NORRIN/APC Conjugated antibody (bs-19062R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19062R-APC
英文名稱1 Rabbit Anti-NORRIN/APC Conjugated antibody
中文名稱 APC標記的諾里病NDP蛋白/早產(chǎn)兒視網(wǎng)膜病蛋白抗體
別    名 EVR2; Exudative vitreoretinopathy 2 (X linked); FEVR; ND; NDP; NDP_HUMAN; Norrie disease (pseudoglioma); Norrie disease protein; Norrin; Norrin precursor; X linked exudative vitreoretinopathy 2 protein; X-linked exudative vitreoretinopathy 2 protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發(fā)育生物學  神經(jīng)生物學  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NORRIN
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009]

Function:
Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the outer nuclear, inner nuclear and ganglion cell layers of the retina, and in fetal and adult brain.

DISEASE:
Defects in NDP are the cause of Norrie disease (ND) [MIM:310600]; also known as atrophia bulborum hereditaria or Episkopi blindness. ND is a recessive disorder characterized by very early childhood blindness due to degenerative and proliferative changes of the neuroretina. Approximately 50% of patients show some form of progressive mental disorder, often with psychotic features, and about one-third of patients develop sensorineural deafness in the second decade. In addition, some patients have more complex phenotypes, including growth failure and seizure. Defects in NDP are the cause of vitreoretinopathy exudative type 2 (EVR2) [MIM:305390]. EVR2 is a disorder of the retinal vasculature characterized by an abrupt cessation of growth of peripheral capillaries, leading to an avascular peripheral retina. This may lead to compensatory retinal neovascularization, which is thought to be induced by hypoxia from the initial avascular insult. New vessels are prone to leakage and rupture causing exudates and bleeding, followed by scarring, retinal detachment and blindness. Clinical features can be highly variable, even within the same family. Patients with mild forms of the disease are asymptomatic, and their only disease related abnormality is an arc of avascular retina in the extreme temporal periphery.

Similarity:
Contains 1 CTCK (C-terminal cystine knot-like) domain.

Database links:

Entrez Gene: 4693 Human

Entrez Gene: 418560 Chicken

Entrez Gene: 612440 Dog

Entrez Gene: 17986 Mouse

Entrez Gene: 363443 Rat

Omim: 300658 Human

SwissProt: Q2KI78 Cow

SwissProt: Q00604 Human

SwissProt: P48744 Mouse

Unigene: 522615 Human

Unigene: 5014 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.xucheq.com 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
廖承宇做受被C22分钟视频| 亚洲精品AV中文字幕在线| 又大又长粗又爽又黄少妇视频 | 久久精品AⅤ无码中文字字幕重口| 午夜精品久久久久久久久| 国产午夜鲁丝片AV无码免费| 亚洲精品一区三区三区在线观看 | 国产产无码乱码精品久久鸭 | 97人妻精品一区二区三区| 日本人妻伦在线中文字幕| 狂飙大嫂是谁扮演的| 久久国产精品久久久久久| 欧美69久成人做爰视频| 国精品人妻无码一区二区三区牛牛| 亚洲爆乳精品无码一区二区三区| 亚洲精品成人区在线观看| 日韩亚洲av人人夜夜澡人人爽| 性大毛片视频| 秘书喂奶好爽一边吃奶一| 丰满熟妇乱又伦| 亚洲AV综合色区无码另类小说| 色噜噜狠狠色综合日日| chinesemature老熟妇高潮| 性少妇freesexvideos高清 | 无码粉嫩小泬无套在线观看A片 | 人人爽人人爽人人片AV| 一本色道久久HEZYO无码| 成人小说亚洲一区二区三区| 免费看又黄又无码的网站| 国产麻豆剧传媒精品国产AV| 最近免费中文字幕大全高清10| 国产成A人亚洲精V品无码| 性一交一乱一乱一视频| 久久国产成人午夜AV影院| 亚洲精品久久久久久中文 | 久久精品中文字幕| you jizz jizz japan日本| 国产亚州精品女人久久久久久| FREEXXXXHD天美传媒A| ,国产精品久久久久久| 妺妺窝人体色WWW看美女|