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Rabbit Anti-MUPCDH/BF350 Conjugated antibody (bs-19107R-BF350)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19107R-BF350
英文名稱1 Rabbit Anti-MUPCDH/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的鈣粘蛋白相關(guān)家庭成員5/μ-protocadherin抗體
別    名 Cadherin-related family member 5; Cdhr5; CDHR5_HUMAN; FLJ 20219; FLJ20219; MU-PCDH; Mu-protocadherin; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Mucin and cadherin-like protein; mucin-like protocadherin.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 85kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MUPCDH
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]

Function:
Acts as a calcium-dependent cell adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver.

Post-translational modifications:
N- and O-glycosylated.

Similarity:
Contains 4 cadherin domains.

Database links:

Entrez Gene: 53841 Human

Entrez Gene: 101138146 Gorilla

Entrez Gene: 100410617 Marmoset (common)

Entrez Gene: 100461892 Orangutan

Omim: 606839 Human

SwissProt: Q9HBB8 Human

Unigene: 165619 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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