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Rabbit Anti-NXN/PE-Cy3 Conjugated antibody (bs-19555R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19555R-PE-Cy3
英文名稱1 Rabbit Anti-NXN/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的NXN蛋白抗體
別    名 FLJ12614; NRX; nucleoredoxin 1; Nucleoredoxin; Nxn; NXN_HUMAN; OTTHUMP00000115356; TRG 4.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NXN
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity)

Subcellular Location:
Cytoplasm > cytosol. Nucleus.

Similarity:
Belongs to the nucleoredoxin family.
Contains 1 thioredoxin domain.

Database links:

Entrez Gene: 64359 Human

Entrez Gene: 531367 Cow

Entrez Gene: 18230 Mouse

Entrez Gene: 360577 Rat

Omim: 612895 Human

SwissProt: A6QLU8 Cow

SwissProt: Q6DKJ4 Human

SwissProt: P97346 Mouse

Unigene: 527989 Human

Unigene: 27915 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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