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Rabbit Anti-PYGO1/PE-Cy3 Conjugated antibody (bs-19692R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-19692R-PE-Cy3
英文名稱(chēng)1 Rabbit Anti-PYGO1/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的PYGO1蛋白抗體
別    名 PYGO 1; PYGO1; PYGO1_HUMAN; Pygopus homolog 1 (Drosophila); Pygopus homolog 1; Pygopus like protein 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PYGO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Involved in signal transduction through the Wnt pathway.

Subunit:
Interacts with BCL9 via The PHD-type zinc finger motiv, and thereby becomes part of the nuclear beta-catenin/TCF complex. Identified in a complex with BCL9L, CDC73, CTNNB1 and PYGO1.Interacts with histone H3 mono-, di- or tri-methylated at 'Lys4' (H3K4me1, H3K4me2, H3K4me3); the interaction is enhanced by the interaction with BCL9.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 PHD-type zinc finger.

Database links:

Entrez Gene: 26108 Human

Entrez Gene: 72135 Mouse

Entrez Gene: 691857 Rat

Omim: 606902 Human

SwissProt: Q9Y3Y4 Human

SwissProt: Q9D0P5 Mouse

Unigene: 256587 Human

Unigene: 273605 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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