吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
人妻忍着娇喘被中进中出视频,中文字幕久久熟女蜜桃,欧美另类69xxxxx
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Perforin/APC Conjugated antibody (bs-20810R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20810R-APC
英文名稱1 Rabbit Anti-Perforin/APC Conjugated antibody
中文名稱 APC標記的穿孔素抗體
別    名 Cytolysin; FLH2; HPLH2; Lymphocyte pore forming protein; Lymphocyte pore-forming protein; MGC65093; P1; PERF_HUMAN; PERF_MOUSE; Perforin 1; Perforin 1 precursor; Perforin 1 preforming protein; Perforin-1; PFP; PGFL; PIGF; PIGF-2; PLGF; Pore forming protein; PRF 1; PRF1; SHGC-10760.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  淋巴細胞  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Perforin
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

Function:
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Subunit:
Monomer, as sobluble protein. Homooligomer. Oligomerization is required for pore formation.

Subcellular Location:
Cytoplasmic granule lumen. Secreted. Cell membrane. Endosome lumen. Stored in cytoplasmic granules of cytolytic T-lymphocytes and secreted into the cleft between T-lymphocyte and target cell. Inserts into the cell membrane of target cells and forms pores. Membrane insertion and pore formation requires a major conformation change. May be taken up via endocytosis involving clathrin-coated vesicles and accumulate in a first time in large early endosomes.

Post-translational modifications:
N-glycosylated.

DISEASE:
Defects in PRF1 are the cause of hemophagocytic lymphohistiocytosis familial type 2 (FHL2) [MIM:603553]; also known as HPLH2. Familial hemophagocytic lymphohistiocytosis (FHL) is a genetically heterogeneous, rare autosomal recessive disorder. It is characterized by immune dysregulation with hypercytokinemia and defective natural killer cell function. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia, hypofibrinogenemia, and neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits, and ataxia. Hemophagocytosis is a prominent feature of the disease, and a non-malignant infiltration of macrophages and activated T lymphocytes in lymph nodes, spleen, and other organs is also found.

Similarity:
Belongs to the complement C6/C7/C8/C9 family.
Contains 1 C2 domain.
Contains 1 EGF-like domain.
Contains 1 MACPF domain.

Database links:

Entrez Gene: 5551 Human

Entrez Gene: 18646 Mouse

Entrez Gene: 50669 Rat

Omim: 170280 Human

SwissProt: P14222 Human

SwissProt: P10820 Mouse

SwissProt: P35763 Rat

Unigene: 2200 Human

Unigene: 240313 Mouse

Unigene: 11206 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久99国产精一区二区三区| ASS白嫩白嫩的少妇PICS| 国产真人无码作爱视频免费| 色婷婷综合久久久中文字幕| 中文字幕亚洲无线码在线一区| 久久精品国产99国产精品| 熟睡人妻被讨厌的公侵犯| 精品久久久久久久免费人妻| 国产乱子伦一区二区三区| 亚洲精品www久久久久久| 99久久99久久免费精品小说| 亚洲熟妇AV一区二区三区| 亚洲AV无码成人精品区| 国产人妻久久精品二区三区特黄| 特级毛片A片久久久久久| 欧美激情综合色综合啪啪五月| 精品无码国产一区二区三区麻豆| 久久久久99精品成人片直播 | 无套熟女AV呻吟在线观看| 十九岁日本电影免费完整版观看| 欧美裸体XXXX极品少妇| 久久精品无码AV| 中文字幕一区二区| 久久久精品欧美一区二区免费| 被公牛日到了高潮| 一本一道久久A久久精品综合| 久久精品国产亚洲av麻豆| 人人摸人人操| 啊灬啊灬啊灬快灬高潮了| 婷婷综合久久中文字幕蜜桃三电影 | 亚洲av无码乱码在线观看性色| 性大毛片视频| 爆乳熟妇一区二区三区| 色综合99久久久无码国产精品| 97在线视频人妻无码| 羞羞漫画在线观看| 一本色道久久综合无码人妻| 色噜噜狠狠一区二区三区果冻| 久久精品A亚洲国产V高清不卡| 日本乱偷人妻中文字幕在线| 无码人妻精品一二三区免费 |