產(chǎn)品編號(hào) | bs-20126R-Gold |
英文名稱1 | Rabbit Anti-MDH2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的線粒體蘋果酸脫氫酶2抗體 |
別 名 | M MDH; Malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase, mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2, NAD; Mor 1; MOR1; OTTMUSP00000026139. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 新陳代謝 線粒體 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 33kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MDH2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Subunit: Homodimer. Subcellular Location: Mitochondrion matrix. Post-translational modifications: Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri-and tetraacetylations. Glucose also increases acetylation by about 60%. Similarity: Belongs to the LDH/MDH superfamily. MDH type 1 family. Database links: Entrez Gene: 4191 Human Entrez Gene: 17448 Mouse Omim: 154100 Human SwissProt: P40926 Human SwissProt: P08249 Mouse Unigene: 520967 Human Unigene: 297096 Mouse Unigene: 1011 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |