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Rabbit Anti-IL-22/BF555 Conjugated antibody (bs-20683R-BF555)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-20683R-BF555
英文名稱(chēng)1 Rabbit Anti-IL-22/BF555 Conjugated antibody
中文名稱(chēng) BF555標(biāo)記的白介素-22抗體
別    名 Interleukin-22; Il22; IL-22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL23; zcyto18.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 免疫學(xué)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-22
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].

Function:
Cytokine that contributes to the inflammatory response in vivo.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-10 family.

Database links:

Entrez Gene: 50616 Human

Entrez Gene: 50929 Mouse

Entrez Gene: 500836 Rat

Omim: 605330 Human

SwissProt: Q9GZX6 Human

SwissProt: Q9JJY9 Mouse

Unigene: 287369 Human

Unigene: 103585 Mouse

Unigene: 195879 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IL-22是白介素-10家族的成員,主要是由激活的T 淋巴細(xì)胞產(chǎn)生的一類(lèi)重要的細(xì)胞因子,除了在Th17細(xì)胞中高表達(dá)之外,在NK和NKT等細(xì)胞中也有表達(dá),在組織損傷修復(fù)以及牛皮癬、肝炎、肺炎、腸炎等慢性炎癥中發(fā)揮重要作用.IL-22是繼IL-6和IL-10之后又一個(gè)參與炎癥反應(yīng)和代謝調(diào)控的細(xì)胞因子,IL-22有可能成為干預(yù)脂肪肝發(fā)生發(fā)展的新方法。
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