吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲精品无码专区,亚洲成av人片一区二区密柚,无码人妻精品一区二区三18禁
Mouse Anti-TNF-alpha/PE-Cy3 Conjugated antibody (bsm-33207M-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bsm-33207M-PE-Cy3
英文名稱1 Mouse Anti-TNF-alpha/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的腫瘤壞死因子-α單克隆抗體
別    名 tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF a ; TNF alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precurso; Tumour Necrosis Factor Alpha.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來(lái)源 Mouse
克隆類型 Monoclonal
克 隆 號(hào) 3A4
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig, Monkey, Insect, Yeast)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17/26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human TNF alpha 77-233aa
亞    型 IgG1
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.

Function:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

Subunit:
Homotrimer. Interacts with SPPL2B..

Subcellular Location:
Cell membrane; Single-pass type II membrane protein.
Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein.
Tumor necrosis factor, soluble form: Secreted.
C-domain 1: Secreted.
C-domain 2: Secreted.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.
The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.

DISEASE:
Genetic variations in TNF are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 7124 Human

Entrez Gene: 21926 Mouse

Omim: 191160 Human

SwissProt: P01375 Human

SwissProt: P06804 Mouse

Unigene: 241570 Human

Unigene: 1293 Mouse




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
zzijzzij亚洲日本少妇jizjiz| 亚洲精品无码AV人在线观看国产| 女人高潮特级毛片| 精品一区二区久久久久久久网站| 我和子发生了性关系视频 | 国产欧美精品一区二区三区| 妓女精品国产噜噜亚洲AV| 全黄裸片一29分钟免费真人版| 国产传媒果冻天美传媒怎么入职 | 亚洲欧美精品午睡沙发| 99好久被狂躁A片视频无码| 无遮挡国产高潮视频免费观看| 亚洲欧美日本韩国| 真人性做爰直播| 久久99精品国产麻豆婷婷| AV无码AV天天AV天天爽| 亚洲精品无码MV在线观看| 国产欧美一区二区精品性色| 亚洲精品国产精品国自产观看| 国产精品99久久久久久宅男| 乳尖乱颤娇喘连连A片在线观看| BL漫画网站| 学长被C哭着爬走又被拉回来| 国内精品久久久久久中文字幕| 十九岁日本电影免费完整版观看| 精品夜夜澡人妻无码AV蜜桃| 无码人妻精品一区二区三区不卡 | 国产成人精品一区二区三区无码| 中文字幕丰满乱孑伦无码专区| 亚洲精品白浆高清久久久久久| 中文无码人妻有码人妻中文字幕| 三上悠亚SSⅠN939无码播放| 国产精品无码久久久久久| 色88久久久久高潮综合影院| 国产男女爽爽爽免费视频| 少妇被粗大的猛烈进出A片久久久| JAPAN少妇洗澡VIDEOS | 国产偷窥盗拍丰满老熟女| 国产偷人爽久久久久久老妇APP| 天天躁日日躁狠狠躁AV中文| 久久久亚洲精华液精华液精华液|