吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国产一区二区三精品久久久无广告,亚洲一区精品无码色成人
Mouse Anti-human CD127-APC/Cy3 Conjugated antibody (bsm-30089M-APC-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bsm-30089M-APC-Cy3
英文名稱1 Mouse Anti-human CD127-APC/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的APC標(biāo)記小鼠抗人CD127單克隆抗體
別    名 CD 127; CD127; CD127 antigen; CDW127; IL 7R alpha; IL 7R; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; IL7R; IL7RA; IL7RA_HUMAN; IL7Ralpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor; Interleukin 7 receptor isoform H5 6; Interleukin-7 receptor subunit alpha.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  干細(xì)胞  淋巴細(xì)胞  t-淋巴細(xì)胞  b-淋巴細(xì)胞  
抗體來源 Mouse
克隆類型 Monoclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Liquid
濃    度 1mg/ml
免 疫 原
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

Function:
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Subcellular Location:
Secreted and Cell membrane.

Post-translational modifications:
N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form.

DISEASE:
Defects in IL7R are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)B(+)NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.
Genetic variations in IL7R are a cause of susceptibility to multiple sclerosis type 3 (MS3) [MIM:612595]. A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological mechanism is regarded as an autoimmune attack of the myelin sheat, mediated by both cellular and humoral immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors influence susceptibility to the disease. Note=A polymorphism at position 244 strongly influences susceptibility to multiple sclerosis. Overtransmission of the major 'C' allele coding for Thr-244 is detected in offspring affected with multiple sclerosis. In vitro analysis of transcripts from minigenes containing either 'C' allele (Thr-244) or 'T' allele (Ile-244) shows that the 'C' allele results in an approximately two-fold increase in the skipping of exon 6, leading to increased production of a soluble form of IL7R. Thus, the multiple sclerosis associated 'C' risk allele of IL7R would probably decrease membrane-bound expression of IL7R. As this risk allele is common in the general population, some additional triggers are probably required for the development and progression of MS.

Similarity:
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 1 fibronectin type-III domain.

Database links:

Entrez Gene: 3575 Human

Omim: 146661 Human

SwissProt: P16871 Human

Unigene: 591742 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
日韩精品人妻中文字幕有码| 天天爽夜夜爽人人爽,qc| 亚洲精品无码久久久久久久| 一本色道久久HEZYO无码| 高清家庭影院| GOGO人体| japanese老熟妇乱子伦视频| 亚洲av无码乱码在线观看性色| 中字幕视频在线永久在线观看免费| 国产精品人成视频免费播放| SPY3WC撒SPY3WC撒尿| 国产传媒果冻天美传媒怎么入职| 动漫3D成人H无码国漫| 国产免费又爽又色又粗视频| 熟妇高潮精品一区二区三区| 偷拍真实夫妇作爱视频| 成人免费ā片在线观看| 香港三级日本三级妇三级| 天天躁日日躁狠狠躁AV中文| 无码人妻一区二区三区在线视频| 五月丁香综合啪啪成人小说| 欧美精品久久久久久久自慰| 黄瓜视频在线观看| 又硬又粗又大一区二区三区视频| 性欧美丰满熟妇XXXX性久久久| 人妻在厨房被色诱 中文字幕| 重囗味SM在线观看无码| 99久久久无码国产精品不卡 | 欧美性激烈粗大精品XXX| 成人免费毛片AAAAAA片| 国产伦孑沙发午休精品| 无码熟熟妇丰满人妻啪啪| 国产日产久久高清欧美一区| 69SEX久久精品国产麻豆| 亚洲毛片| 国产偷人爽久久久久久老妇APP| 亚洲中文字幕无码爆乳AV| 妈妈的朋友2在线观看| 日韩人妻精品一区二区三区视频| 无码AV免费毛片一区二区| 亚洲精品国产电影|