產(chǎn)品編號(hào) | bs-24104R-Gold |
英文名稱1 | Rabbit Anti-Nucleoplasmin 2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的核仁磷酸蛋白2抗體 |
別 名 | NPM2; NPM2_MOUSE; nucleophosmin/nucleoplasmin, 2; nucleoplasmin 2; Nucleoplasmin-2. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 發(fā)育生物學(xué) 染色質(zhì)和核信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 24kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse Nucleoplasmin 2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: NPM2 (Nucleophosmin/Nucleoplasmin 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and enzyme binding. An important paralog of this gene is NPM1. Function: Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. Subunit: Homopentamer, when bound to H2A-H2B dimers only. Homodecamer of two stacked pentamers, when bound to H2A-H2B dimers and H3-H4 tetramers simultaneously (By similarity). Subcellular Location: Nucleus. Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm. Similarity: Belongs to the nucleoplasmin family. Database links: Entrez Gene: 10361?Human Entrez Gene: 328440?Mouse Omim: 608073?Human SwissProt: Q86SE8?Human SwissProt: Q80W85?Mouse Unigene: 131055?Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |