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Mouse Anti-human CD3/PE Conjugated antibody (bsm-30092M-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 25T  50T  100T
25T/260.00元
50T/420.00元
100T/680.00元
大包裝/詢價

產(chǎn)品編號 bsm-30092M-PE
英文名稱1 Mouse Anti-human CD3/PE Conjugated antibody
中文名稱 PE標記的小鼠抗人CD3單克隆抗體
別    名 CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.  
規(guī)格價格 25T/260元 購買    50T/420元 購買    100T/680元 購買    大包裝/詢價
說 明 書 25T  50T  100T
研究領域 腫瘤  細胞生物  免疫學  細胞表面分子  t-淋巴細胞  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 HIT3b
交叉反應 Human, 
產(chǎn)品應用 Flow-Cyt=10ul/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原 KLH conjugated synthetic peptide derived from human CD3
亞    型 Mouse IgG2a, k
純化方法 affinity purified by Protein G
儲 存 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存條件 Store at 2-8℃. Protect from light. Avoid freezing.
產(chǎn)品介紹 background:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

Function:
The CD3 complex mediates signal transduction.

Subunit:
he TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain. Contains 1 ITAM domain.

Database links:


Entrez Gene: 916 Human

Entrez Gene: 12501 Mouse

Omim: 186830 Human

SwissProt: P07766 Human

SwissProt: P22646 Mouse

Unigene: 3003 Human

Unigene: 210361 Mouse




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD3 epsilon 參與T淋巴細胞介導,主要用于免疫排斥方面的研究.
產(chǎn)品圖片
scatter diagram showing peripheral blood lymphocytes stained with bsm-30092M-PE. The cells were incubated with the antibody (bsm-30092M-PE, 10 μl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
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